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Updated: Sep 10, 2025

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
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死亡率が低い研究が 倫理的に正当化されるでしょうか?

Dick Willems1, Hanno Tan2, Nikolaos Dagres3

  • 1Department of Ethics, Law and Humanities, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Journal of medical ethics
|August 26, 2025
PubMed
まとめ

死亡率のエンドポイントを持つ非劣等性 (NI) 試験には,倫理的な正当性,患者にとって受け入れられる明確なNIマージン,および優等性設計に対する明示的な根拠が必要です. 倫理的な反省は これらの裁判に不可欠です

キーワード:
バイオ統計臨床試験倫理について倫理委員会,研究倫理,研究

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