関連する実験動画

Updated: Sep 10, 2025

Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes
10:03

Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes

Published on: November 11, 2016

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特定のがん免疫療法を強化するために,c-MYCベースの遺伝子回路プラットフォームで腫瘍のマイクロ環境を再プログラムする

Hengji Zhan1,2,3, Hongjin Wang1,2,3, Bolin Pan1,2,3

  • 1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Nature communications
|August 26, 2025
PubMed
まとめ

この研究は,がん免疫療法における腫瘍異質性を克服するための新しいc-MYCセンシング回路 (cMSC) とエクソソームシステム (CtC) を導入しています. このアプローチは,異常なc-MYCレベルを感知し,免疫反応を強化することで,すべての癌細胞をターゲットにします.

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