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Updated: Sep 10, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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カピリポシドAは,NF- kB/ TLR4およびアポプトシス経路の調節により,糖尿病性腎臓病を緩和する

Xueli Man1,2, Luping Wang1,2, Huajun Liao3

  • 1Department of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, Zhejiang, China.

Scientific reports
|August 26, 2025
PubMed
まとめ

カピリポシドA (LC- A) は,主要な炎症および酸化ストレス経路を標的として,糖尿病性腎不全 (DN) の治療において有望である. この天然化合物は,マウスモデルで腎臓損傷マーカーを効果的に減らし,腎臓機能を改善しました.

キーワード:
アポプトシス経路カピリポシドA糖尿病性腎臓病分子ドッキングNF-κB/TLR4経路についてネットワーク薬理学

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