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Updated: Sep 10, 2025

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PKM2は,内皮細胞におけるANGPT2による血管新生活性化を調節する

Qiangqiang Ge1, Jianan Guo2,3, Liyuan Ye1

  • 1Shangyu People's Hospital of Shaoxing, Shaoxing University, Shaoxing, 312000, China.

Scientific reports
|August 26, 2025
PubMed
まとめ

パイルー酸キナーゼ型M2 (PKM2) は,腫瘍の成長における重要なプロセスである内皮細胞の増殖,移転,および血管新生を駆動する. PKM2とその下流エフェクタである ANGPT2をターゲットにすることで,血管新生に関連する疾患に対する潜在的な治療戦略が提供されます.

キーワード:
ANGPT2 について血管新生内皮細胞グライコリシスPKM2 について

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