関連する実験動画

Updated: Sep 10, 2025

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
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Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

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5 - ALA媒介のPDTは,カスパース-1/GSDMD経路をターゲットにすることで,結腸直腸がん細胞のピロプトーシスを誘発する

Ding-Yuan Zhang1, Zeqing Gu1, Luyao Shi1

  • 1Harbin Medical University Cancer Hospital, Harbin, China.

Lasers in medical science
|August 26, 2025
PubMed
まとめ

5 - アミノレブリン酸 (5- ALA) 光力学療法 (PDT) は,結腸直腸がん細胞における細胞死の一種であるピロプトーシスを引き起こす. これはカスパース-1/ガスダーミンD経路を通じて発生し,CRC治療の可能性を秘めています.

キーワード:
大腸がんGSDMD について光力学療法ピロプトーシス

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