生まれながらの心臓病に関連した遺伝的変異:民族とサブタイプ特有の感受性のメタ分析

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Updated: Sep 10, 2025

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
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Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

Published on: March 10, 2020

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Hae Sung Chon1, Ji Wan Park1

  • 1Department of Medical Genetics, Hallym University College of Medicine, Chuncheon, Republic of Korea.

Circulation. Genomic and precision medicine
|August 27, 2025
PubMed
まとめ

このメタ解析では,先天性心疾患 (CHD) と関連した有意な遺伝的変異が特定され,さまざまな集団とサブタイプにおけるリスク推定が精製されました. これらの発見は,心臓発作と代謝に関与する遺伝子を強調し,心臓病における潜在的精密医療の応用を示しています.

キーワード:
人種葉酸心臓障害,先天性メタ解析ポリモルフィズム,単一のヌクレオチド

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