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Updated: Sep 10, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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ERBINは,TGF-βシグナル伝達を抑制することにより,上皮細胞の可塑性を抑制する

Chao Li1, Gerard van der Zon1, Peter Ten Dijke1

  • 1Oncode Institute and Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), The Netherlands.

FEBS letters
|August 27, 2025
PubMed
まとめ

ERBINは,変形成長因子β (TGF-β) と表皮成長因子受容体 (EGFR) のシグナリングを阻害することによって,上皮からメゼンキマへの移行 (EMT) を抑制する. このタンパク質は細胞の移転と癌の進行を制御する重要な要素です.

キーワード:
エルビン皮質の成長因子受容体エピテリアからメゼンキマへの移行細胞外信号調節キナーゼ信号変換変換成長因子-β

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