ローカル麻酔剤の相互作用を評価する - 根の歯における連続的ケラ化 - 試験

Lokhasudhan Govindaraju¹, Sangkeetha Gnanasekaran¹, Mathan Rajan Rajendran¹

¹Department of Conservative Dentistry and Endodontics, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research (SRIHER - DU), Chennai, Tamil Nadu, India.

Journal of conservative dentistry and endodontics

|August 27, 2025

まとめ

2%のリグノカインHClと連続灌 (塩酸塩酸ナトリウムとEDTA) を使った肺内麻酔は,根管治療中に最も少ない残骸を生成しました. 4%のアルティカインHClで,より高い破片レベルが観察されました.

科学分野:

エンドドンティクス
歯科材料科学
局所麻酔

背景:

反応しない歯の根管治療には,局所麻酔薬 (LAs) の腸内注射が不可欠です.
LAと内歯灌剤の相互作用は十分に理解されていません.
LAと灌剤の相互作用による破片の形成を調査することは,手順の安全性にとって不可欠です.

研究の目的:

局所麻酔溶液が内歯灌剤と相互作用するときの破片の形成を評価する.
異なる局所麻酔剤 (リグノカインHCl vs. アルティカインHCl) を使って破片の形成を比較する.
灌プロトコル (連続ケレーションと連続ケレーション) がゴミに与える影響を評価する.

主な方法:

16個の単根の下前歯が使用された.
2% のリグノカイン HCl または 4% のアルティカイン HCl を用いて,腹腔内麻酔を行った.
歯は3%の塩化ナトリウム (NaOCl) と17%のエチレンジアミネトラエセチック酸 (EDTA),またはNaOClを1−ヒドロキシエチリデン−1, 1−二フォスフォン酸 (HEDP) で灌し,その後,スキャニング電子顕微鏡 (SEM) 分析を行った.

主要な成果:

SEM分析では,2%のリグノカインHClと連続灌 (NaOClとEDTA) で残渣の形成が最小であることが示された.
根の頂上三分の一は,すべてのグループでかなり高い量の破片を示しました.
2%のリグノカインHClと比較して,4%のアルティカインHClは一貫してより大きな破片の蓄積をもたらしました.

結論:

NaOClとEDTAによる連続灌は,2%のリグノカインHClを使用すると,破片の形成を最小限に抑えます.
NaOClとHEDPによる継続的なケレーションは,連続灌と比較してより多くの破片を生成します.
4% Articaine HClは,使用された灌プロトコルに関係なく,破片の形成の増加と関連しています.

キーワード:

アルティカイン塩化物継続的なケレーションイントラパルパル麻酔リドカイン塩化物根の歯質スキャン電子顕微鏡連続灌

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