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エクトピック・アドレノコルチノトロピン分泌肺がん腫瘍の切除後の急速腎上腺縮

  • 0Division of Diabetes, Endocrinology and Metabolism, Section of Endocrinology and Investigative Medicine, Imperial College London, London W12 0NN, UK.
Jcem Case Reports +

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2025年8月27日

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2025年8月27日

PubMedで要約を見る

まとめ

この要約は機械生成です。

神経内分泌腫瘍からの子宮外アドレノコルチコトロピン (ACTH) の分泌は,カッシング症候群を引き起こす可能性があります. この症例は,迅速な腎上腺縮と,手術後の早期の下垂体-腎上腺 (HPA) 軸の回復を強調し,早期の術後検査の仮定に異議を唱えます.

科学分野

  • 内分泌学
  • 腫瘍学
  • 神経外科

背景

  • 神経内分泌腫瘍 (NETs) による子宮外アドレノコルチコトロピン (ACTH) の分泌は,ACTH依存のクッシング症候群の珍しい原因である.
  • 長期にわたるACTHとコルチゾールの過剰生産は,通常,手術後の下垂体- 上腺 (HPA) 軸抑制につながります.
  • 短サイナクテン検査 (SST) を用いたHPA軸の回復の早期の術後の評価は,下垂体皮質栄養抑制および潜在的に多発性副腎のため,信頼性が低い場合があります.

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