レミザロラムとフェンタニルの有効性 vs フェンタニルとミダゾラムの有効性 検診大腸内視鏡検査における鎮静作用: ランダム化比較試験

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Updated: Sep 10, 2025

Application of Dixon's Up-and-Down Design to Estimate the Minimum Alveolar Concentration of Sevoflurane in Rats with Refined Movement Classification
03:02

Application of Dixon's Up-and-Down Design to Estimate the Minimum Alveolar Concentration of Sevoflurane in Rats with Refined Movement Classification

Published on: July 25, 2025

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Andrea C Armbrecht1,2, Bojan Kovacevic3, Maria Dyrehave Rasmussen4

  • 1Herlev, Herlev Hospital, Herlev, Denmark.

Endoscopy international open
|August 27, 2025
PubMed
まとめ

レミマゾラムとフェンタニルは,ミダゾラムと比較して,大腸内視鏡検査において優れている鎮静効果をもたらし,処置を短縮し,患者の回復を改善します. この組み合わせは,スクリーニング・コロノスコーピーの際に患者の快適さと満足度を高めます.

キーワード:
CRCスクリーニング大腸がん内視切除 (ポリペクトミー,ESD,EMRc, ...)内視鏡 下部 消化管

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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea07:54

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
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Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
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