女性におけるガンの世界的な負担,1990-2021年:GBD 2021研究からの体系的な分析

Yun Mao¹, Yebo Gao², Yongjie He³

¹Department of Oncology, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.

Frontiers in oncology

|August 27, 2025

まとめ

乳がんが増加し,子宮頸がんは低所得地域を不釣り合いに影響しています. 格差を克服するには HPVワクチン接種,スクリーニング,肥満管理が必要です

科学分野:

腫瘍学
流行病学について
公衆衛生

背景:

女性のがん (乳がん,子宮頸がん,子宮がん,卵巣がん) は,世界的な健康問題です.
その負担や傾向や格差を理解することは効果的な介入に不可欠です

研究の目的:

1990年から2021年までの女性がんの世界的な負担,格差,傾向を評価する.
重要な要因と効果的な介入戦略を特定する.

主な方法:

世界疾病負担 (GBD) 研究 (1990-2021) と最近の報告から得られたデータを使用した.
社会人口指数 (SDI) によって層分かれ,204カ国で発生率,死亡率,障害調整寿命 (DALYs) を分析した.
リスク因子と医療へのアクセスを調べるために回帰と時空分析を用いた.

主要な成果:

乳がんの発生率は28%増加し, 高いSDIとライフスタイル要因と強く相関しています.
子宮頸がんの負担は SDIとネガティブに相関し,世界的に死亡率が低下しているにもかかわらず,低,中所得地域では継続しています.
子宮がんの発生率は肥満により増加し,卵巣がんの死亡率は遅い診断により高いままです. HPV,たばこ,生殖行動が主なリスクです.

結論:

世界的な女性がんの負担は深刻な公衆衛生上の課題と医療へのアクセスにおける不平等を強調しています
優先すべき介入はHPVワクチン接種,アクセス可能なスクリーニング,肥満管理です.
女性の癌の負担を軽減するために公平に焦点を当てたデータ主導の政策は不可欠です

キーワード:

世界的な病気の負担乳がん子宮頸がん女性がんグローバル・ヘルス・エクイティ卵巣がん子宮がん

さらに関連する動画

07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

400

04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.3K

関連する概念動画

01:21

Cancer Survival Analysis

453

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

453

01:24

Disorders of the Female Reproductive System

489

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

489

01:08

Prevalence and Incidence

802

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...

802

01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

8.0K

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

8.0K

02:18

Cancer

49.5K

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

49.5K

01:33

Cancer-Critical Genes I: Proto-oncogenes

9.1K

関連する実験動画