精神疾患の治療のためのケタミン使用に関するインドの文献の体系的なスコープレビュー
Swarndeep Singh1, Bhagwat Singh Rathore1, Pankaj Verma1
1Department of Psychiatry, Vardhman Mahavir Medical College and Safdarjung Hospital, Delhi, India.
Industrial psychiatry journal
|August 27, 2025
まとめ
このレビューは,インドの精神疾患に対するケタミンの研究をマッピングし,代替投与経路への関心が高まっていることを発見しました. ケタミン療法のプロトコルと安全性を最適化するために,より厳格な研究が必要です.
科学分野:
- 精神科
- 薬理学について
- 臨床研究
背景:
- ケタミンは様々な精神疾患の 潜在的な治療法として登場しています
- インドの現在の研究環境を理解することは 臨床応用に不可欠です
研究 の 目的:
- ケタミンの精神疾患に関する既存の研究を体系的に検討し,マッピングする.
- 研究のギャップを特定し,将来の調査を導く.
主な方法:
- PubMed,Scopus,および Clinical Trials Registry of Indiaで包括的な電子文献検索が行われました.
- 公開された研究 (症例報告,シリーズ,無制御調査,レビュー,RCT) と進行中の試験プロトコルを含む.
主要な成果:
- 20件の研究と29件の試験プロトコルが特定され,主に治療抵抗性うつ病と自殺傾向に焦点を当てた.
- 試験プロトコルでは,口服と皮下経路への関心を示している.
- 計画されたランダム化比較試験 (RCT) の有意な数は試験プロトコルに記載されています.
結論:
- インドでは精神疾患に対するケタミンの研究が増加しており,様々な投与経路を探求する方向に変化しています.
- 精神医学におけるケタミンの有効性,安全性,治療用途を最適化するために,さらに方法論的に厳格な研究が不可欠です.
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