メニエール病におけるGoreisanの有効性
1Otolaryngology-Head and Neck Surgery, Osaka Metropolitan University, Osaka, JPN.
Cureus
|August 27, 2025
まとめ
カンポの薬であるGoreisanは,メニエールで気まぐれの頻度を有意に減少させた.
科学分野:
- 神経学
- 統合医療
- 薬理学について
背景:
- メニエール病 (Ménière's disease,MD) は,気まぐれ,耳鳴り,聴覚障害を特徴とする慢性的な内耳疾患である.
- MDの現在の治療はしばしば症状管理に焦点を当てており,病気の修正の選択肢は限られています.
研究 の 目的:
- メニエール病の症状の管理における 伝統的な日本薬草のゴリーサンの有効性を評価する.
- MD患者における頭の頻度,頭の重度,聴覚機能に対するGoreisanの影響を評価する.
主な方法:
- 164人のメニエール病患者の遡及分析 (2017年4月 - 2022年3月)
- Goreisanで治療された52人の患者と,利尿剤治療を受けなかった31人の患者との比較
- めまい頻度,めまい障害 inventory (DHI) のスコア,そして聴覚機能の評価を12ヶ月間行いました.
主要な成果:
- ゴレイサン群では2, 6, 12ヶ月で気まぐれが有意に減少した.
- ベタヒスティンとライフスタイルの変化が役立つことを示す.
- 聴覚機能の有意な変化はGoreisanグループでは観察されなかった.
結論:
- メニエール病における頭の頻度を減らすための安全で効果的な治療法である可能性があります.
- GoreisanはMD患者の聴覚機能を改善しないようです.
- Goreisanの有効性を検証するには,さらなるプラセボ対照試験が必要である.
さらに関連する動画
10:27In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
10.7K
09:26A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
Published on: March 23, 2016
19.7K
関連する概念動画
Mitral Regurgitation III: Medical Management
30
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
30
Myasthenia Gravis: Overview and Treatment
1.9K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.9K
Rheumatic Heart Disease III: Medical Management
32
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
32
Mitral Stenosis III: Medical Management
21
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
21
Heart Failure Drugs: Inotropic Agents
717
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
717
Open Angle Glaucoma: Treatment
561
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
561
