良性 前立腺 増殖 (BPH) の 男性 の 中 で,アンドロパウズ の 症状 と テストステロン レベル と 下部 尿路 の 症状 の 相互 関係: 横断 研究
Rishikant Gyani1, Apul Goel1, Satyanarayan Sankhwar2
1Urology, King George's Medical University, Lucknow, IND.
Cureus
|August 27, 2025
まとめ
良性前立腺増殖 (BPH) の男性はしばしばアンドロパウスの症状と低テストステロンレベルを経験し,これは下部泌尿器系症状 (LUTS) の重症度と相関しています. 相互に関連した状況の管理には 総合的な評価が不可欠です
科学分野:
- 泌尿器科
- アンドロロジー
- 内分泌学
背景:
- 良性前立腺増殖 (BPH) は年配の男性に多く見られます.
- アンドロパウスの症状とテストステロンの値低下は,高齢の男性でも一般的です.
- BPH,アンドロパウズ,およびテストステロンレベルの関係については,さらなる調査が必要です.
研究 の 目的:
- 症状のあるBPHの男性におけるアンドロパウスの症状の流行を決定する.
- テストステロンのレベルを評価するために
- アンドロパウスの症状,テストステロン濃度,下部泌尿器系症状 (LUTS) の重度の相関を調査する.
主な方法:
- BPH誘発のLUTSを患った50歳以上の男性183人が登録されました.
- アンドロパウスの症状は,男性のアンドロパウスの症状自己評価アンケート (MASSQ) を使用して評価されました.
- テストステロンレベルは,化学発光免疫測定法で測定され,LUTSと勃起機能は,IPSSとIIEF-15でスコア付けされました.
主要な成果:
- 中等から重度のアンドロパウスの症状の高頻度 (平均スコア57. 24±12. 62) が観察されました.
- LUTSの重症度とアンドロパウスの症状スコア (p < 0. 001) の間に有意な正の相関が認められた.
- テストステロンの濃度の低下は,軽度のLUTS (285. 94 vs 544. 09 ng/ dL) と比較して重度のLUTSと関連していました. 糖尿病や高血圧などの併発症は LUTSと勃起不全を悪化させた.
結論:
- アンドロパウスの症状は,BPHの男性では非常に一般的です.
- テストステロン濃度の低下は,LUTSの重症度の増加と関連しています.
- ホルモン状態と尿路の健康に関する統合的治療は,BPHの高齢者に対して推奨されます.
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