関連する実験動画
Updated: Sep 10, 2025

08:25
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
2.9K
クロルヘキシジン誘発接触アナフィラキシー
Federico Sandoval Morales1, Fabien Pelletier1, François Aubin1
1Dermatology Department, Allergy Unit, Besançon University Hospital, Besançon, FRA.
Cureus
|August 27, 2025
まとめ
重度の手術前アナフィラキシスは 常用抗菌剤であるクロルヘキシジンによって引き起こされます 危険にさらされている患者を特定し,この広く使用されている薬剤に対する潜在的に致命的な反応を防ぐには,警戒心と手術前のスクリーニングが不可欠です.
科学分野:
- 麻酔科
- アレルギーと免疫学
- 手術 の 安全性
背景:
- クロルヘキシジンは,広範囲の抗菌性を持つ,広く使用されている消毒剤です.
- クロルヘキシジンの繰り返し曝露は,過敏反応を引き起こし,過敏化につながる可能性があります.
- 術後のアナフィラキシスは 稀だが重症な合併症で クロルヘキシンがトリガーとして 増加している.
関連する概念動画
Allergic Reactions
28.6K
Overview
28.6K
Hand hygiene
4.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
4.1K
Hypersensitivities
1.0K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
1.0K
Allergic Drug Reactions
978
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
978
Desensitization and Tachyphylaxis
2.2K
Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
2.2K
Nucleophilic Aromatic Substitution: Elimination–Addition
4.1K
Simple aryl halides do not react with nucleophiles. However, nucleophilic aromatic substitutions can be forced under certain conditions, such as high temperatures or strong bases. The mechanism of substitution under such conditions involves the highly unstable and reactive benzyne intermediate. Benzyne contains equivalent carbon centers at both ends of the triple bond, each of which is equally susceptible to nucleophilic attack. This 50–50 distribution of products is...
4.1K

