マグネシウム レベル と 歯周病 の 関係: 体系 的 レビュー
Tomas Cruz-Velasquez1, Alain Raimundo Rodríguez-Orozco2
1Institute of Chemical Biological Research, Michoacan University of San Nicolas de Hidalgo, Morelia, MEX.
Cureus
|August 27, 2025
まとめ
マグネシウムの摂取量と血中濃度は,炎症と重症を軽減して歯周病を予防する. 適切なマグネシウムと健康的なマグネシウム/カルシウム比を維持することは 歯茎の健康にとって重要です
科学分野:
- 口腔 衛生
- 栄養学
- 免疫学
背景:
- 歯周病には 微生物の不均衡と 免疫機能の過剰が伴う
- 微量栄養素,特にマグネシウムの欠乏は歯周病の進行に影響を与える可能性があります.
- マグネシウムの役割を理解することは この炎症状態の管理に不可欠です
研究 の 目的:
- マグネシウム濃度 (血液と食事) とマグネシウム/カルシウム比と歯周病を関連付ける証拠を体系的に検討する.
- マグネシウムの歯周病指標と罹患率との関連に関する発見をまとめます.
- 糖尿病やマグネシウムの抗炎症効果などの全身的関連を調べる
主な方法:
- PubMed,コクラン図書館,Google Scholarの体系的な文献検索 (2024年5月までの開始).
- 成人を対象とした観察的および実験的研究が10件含まれていた.
- PRISMAのガイドラインに従って,研究異質性によるナラティブ・シンセシスを利用しました.
主要な成果:
- 高いマグネシウム濃度は,探知ポケットの深さ,臨床的結合喪失,および歯周炎の有病率と逆相関しています.
- 良好なマグネシウム/カルシウム比は,疾患の進行に対する保護効果を示した (ORは低比で6. 28).
- 糖尿病の歯周炎患者ではマグネシウムの減少が観察され,治療後の改善が認められた.
結論:
- マグネシウムは歯周病の健康に 保護的な役割を果たします
- 適切なマグネシウム濃度とバランスの取れたMg/Ca比は,歯周炎のリスクと重症度を軽減することができます.
- これらの発見を確認し,サプリメント/食事戦略を導くために,さらなる大規模な試験が必要である.
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