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Updated: Sep 10, 2025

Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model
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シノヴィウムと軟骨との相互作用を調節する先天免疫経路の活性化

Peter Linde1, Lyndah Chow1, Isabella Sabino1

  • 1Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.

Frontiers in bioengineering and biotechnology
|August 27, 2025
PubMed
まとめ

Toll-like受容体 (TLR) またはSTING経路によるメゼンキーマストロマ細胞 (MSC) の活性化により,関節細胞との相互作用が変化します. この前活性化は,マクロファージ,シノビオサイト,コンドロサイトにおけるサイトカインの分泌と遺伝子発現に影響を与え,MSC治療に対する細胞特有の反応を示唆する.

キーワード:
スティングメゼンキマ・ストロマ細胞骨関節炎パターン認識レセプター再生療法トール型受容体

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