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Updated: Sep 10, 2025

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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糖尿病の病原性におけるミトコンドリア機能の役割

Bo Qin1,2, Yiying Wang1,2, Jinlong Ding1,2

  • 1Shaoxing Maternity and Child Health Care Hospital, Shaoxing, China.

Frontiers in endocrinology
|August 27, 2025
PubMed
まとめ

ミトコンドリア機能障害は,エネルギー代謝を低下させ,酸化ストレスを増加させ,インスリン抵抗性を引き起こすことで,糖尿病に大きく寄与する. ミトコンドリアを標的とした治療は 糖尿病の治療に有望な戦略です

キーワード:
糖尿病 (DM)エネルギー代謝 (EM)インスリン感受性 (IS)ミトコンドリア機能 (MF)酸化ストレス (OS)

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