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Updated: Sep 10, 2025

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GPR34 デウビキチナーゼUSP8により安定化 ATCのフェロプトーシスを抑制する

Bokang Yan1,2,3, Jiaxing Guo4, Meiyuan Huang3

  • 1Institute of Large-Scale Scientific Facility and Centre for Zero Magnetic Field Science, Beihang University, Beijing 100191, China.

Mediators of inflammation
|August 27, 2025
PubMed
まとめ

Gタンパク質結合受容体34 (GPR34) は,アナプラスティック甲状腺がん (ATC) で上位調節され,腫瘍の成長を抑制し,フェロプトーシスを促進します. GPR34またはそのデウビキチン酵素USP8を標的とした治療は,ATCの有望な治療戦略です.

キーワード:
ATC についてDUB-IN-3 についてGPR34 についてUSP8 についてフェロプトーシス

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