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Updated: Sep 10, 2025

Targeted in Situ Mutagenesis of Histone Genes in Budding Yeast
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ハンジループ変異によるc-Src SH3ドメインの交換を理解する

M Carmen Salinas-Garcia1, Marina Plaza-Garrido1, Jose C Martinez2

  • 1Department of Chemistry and Physics, University of Almeria, Agrifood Campus of International Excellence (ceiA3) and CIAMBITAL, Carretera de Sacramento s/n, 04120 Almeria, Spain.

Acta crystallographica. Section D, Structural biology
|August 27, 2025
PubMed
まとめ

c-Src SH3ドメインを調査した研究者は,c-SrcとAbl SH3タンパク質のループ領域を交換した. ループの組成は安定性と3Dドメインの交換に影響しますが,ダイマー形成の唯一の要因ではありません.

キーワード:
3Dドメインの交換SH3ドメインクローズド/プライマリーインターフェースハンドルループオープン/二次インターフェース

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