固体腫瘍におけるELK1のメカニズムの洞察と臨床的影響:ナラティブレビュー

Georgios Kalampounias1,2, Theodosia Androutsopoulou1, Panagiotis Katsoris1

  • 1Laboratory of Cell Biology, Division of Genetics, Cell and Developmental Biology, Department of Biology, School of Natural Sciences, University of Patras, 26504 Patras, Greece.

Cells
|August 27, 2025
PubMed
まとめ

RAS-RAF-MEK-ERKシグナルによって活性化される転写因子ELK1は,早期の遺伝子を制御することで,がんの進行を促します. 複数の癌においてその発現が増加することは,腫瘍発生における腫瘍発生の可能性と重要性を強調しています.

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