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Updated: Sep 10, 2025

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
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青少年 と 若者 の 肺 癌 症 (AYA): まだ 見過ごさ れ て いる 臨床 分野

Alice Laffi1, Laura Pala1,2, Chiara Catania1,3

  • 1Division of Medical Oncology, Humanitas Gavazzeni, 24125 Bergamo, Italy.

Current oncology (Toronto, Ont.)
|August 27, 2025
PubMed
まとめ

肺癌 (PC) は若年および若年成人ではまれである. このレビューは,AYAの理解と治療を改善するための重要な知識のギャップと緊急の必要性を強調しています.

キーワード:
AYA についてネットワーク肺がん剤神経内分泌腫瘍

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
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