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Updated: Sep 10, 2025

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
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Aphrocallistes Vastus Lectinを発現する腫瘍性ワクチンウイルスは,ACSS2/TFEB媒介によるオートファギーと脂質蓄積を通じて肝細胞癌の代謝を調節する

Qiang Wang1, Simeng Zhou1, Yin Wang1

  • 1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Marine drugs
|August 27, 2025
PubMed
まとめ

肝臓がん (HCC) に対する腫瘍解毒ウイルス治療は,がん細胞の代謝をターゲットにすることで強化することができます. 新しいウイルス (oncoVV-AVL) は,ACSS2/TFEB経路を利用して,脂質の蓄積を引き起こし,グルコースの使用を抑制し,それによって腫瘍の成長を抑制します.

キーワード:
ACSS2 についてアフロカリステス・ヴァストス・レクチンオートファジー腫瘍性ワクチンウイルス

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