開発途上国における不良薬剤反応報告に関する病院薬剤師の見解:比較試験
Javeria Khalid1, Tarilate Temedie-Asogwa1, Marjan Zakeri1,2
1Department of Pharmaceutical Health Outcomes and Policy, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Pharmacy (Basel, Switzerland)
|August 27, 2025
まとめ
米国とパキスタンの病院の薬剤師は,薬剤の副作用 (ADR) の報告に対する知識と態度が類似しています. しかし,システム上の障壁により 開発途上国での報告が難しくなり, 対応策が求められています.
科学分野:
- 薬用警戒について
- 薬物安全性
- 医療サービス研究
背景:
- 薬の副作用は患者の安全に重大なリスクをもたらし,世界的に医療費を増加させます.
- 病院の薬剤師は薬の管理に重要な役割を果たし,ADRの報告を改善する鍵です.
- ADRの報告不足は,特に薬用警戒システムが発達していない途上国において重大な問題である.
研究 の 目的:
- 米国 (先進国) とパキスタン (途上国) の病院の薬剤師の知識,態度,認識された障壁,およびADR報告の促進者を比較する.
主な方法:
- 前もって検証されたアンケートを使用して,少なくとも1年間の経験を持つ病院の薬剤師に横断調査が行われました.
- 参加者を募集するために,便利なサンプリングが採用されました.
- 151人の薬剤師 (51人はアメリカ,100人はパキスタン) からデータを収集した.
主要な成果:
- 米国の薬剤師とパキスタンの薬剤師の知識 (p=0. 193) や態度 (p=0. 379) には大きな違いは見られなかった.
- ADR報告の障壁は,個人レベルとシステムレベルの両方に影響を及ぼし,米国と比較してパキスタンではより顕著でした.
- 特定されたファシリテーターには,モバイル報告アプリケーション,専門的なトレーニング,ユーザーフレンドリーな報告ツールが含まれています.
結論:
- 開発途上国と先進国の薬剤師は,ADR報告に対する知識とポジティブな態度を比較しています.
- パキスタンのような資源の限られた環境では,環境特有の障壁が ADR 報告に大きく影響します.
- 介入は地元の病院のインフラに合わせて,特に開発途上国でのADR報告を強化する必要があります.
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