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Updated: Sep 10, 2025

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
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キヌルレニンは,内皮からメセンキマへの移行,骨質分化およびAhR活性化を通じて,リン酸誘発内皮カルシフィケーションを促進する

Martina Molinaro1, Mario Cozzolino1, Paola Ciceri1

  • 1Laboratory of Experimental Nephrology, Department of Health Sciences, University of Milan, 20142 Milan, Italy.

Toxins
|August 27, 2025
PubMed
まとめ

キヌレニンは,アリル炭化水素受容体 (AhR) 経路を活性化することによって,末期腎疾患 (ESRD) の高リン酸誘発性血管カルシフィケーションを悪化させる. この発見はキヌレニンを強調しています.

キーワード:
AhR についてエンドMTカルシフィケーション内皮細胞キヌレニンオステオブラストの分化リン酸

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