妊娠年齢の幅の広い範囲で幼児の早期神経発達

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妊娠年齢の幅の広い範囲で幼児の早期神経発達

Peggy H Y Chan^1,2, C M Lai², H S Lam¹

¹Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong SAR, China.

Journal of developmental and behavioral pediatrics : JDBP

|August 27, 2025

まとめ

妊娠年齢 (GA) は乳児の発達に好影響を与える. 認知能力,言語能力,運動能力が少しずつ改善されます言語能力は早産に最も敏感です

科学分野:

神経科学
発達に関する小児科
幼児心理

背景:

神経の発達は子宮内環境と子宮外環境によって影響を受けます
妊娠年齢 (GA) は,早産児と早産児の両方の脳発達と神経発達における重要な要因です.

研究の目的:

幅広い妊娠年齢 (GA) が認知,言語,運動の発達に及ぼす影響を包括的に検討する.
幼児の様々な発達領域に対する GAの微妙な影響を理解する.

主な方法:

GAの24週から41週間の間に生まれた454人の乳児の分析
幼児と幼児の発達に関するベイリースケール (Bayley Scales of Infant and Toddler Development),第3版 (ベイリーIII) を用いて認知,言語,運動の発達を評価する.
線形とロジスティック混合効果モデルの適用で,GAと発達上の結果との関連を分析する.

主要な成果:

妊娠年齢 (GA) は,評価されたすべての発達領域 (認知,言語,運動) と小さな,しかし有意な正の関連を示した.
認知能力と言語能力のスコアが0. 6ポイント上昇し,ベイリーIIIで運動能力のスコアが0. 62ポイント上昇した.
幼児の受容性コミュニケーションの遅延率は13%減少しました.

結論:

妊娠年齢 (GA) は,認知,言語,運動の発達に,幅広く影響を与える.
言語の発達,特に受容的コミュニケーションは,早産の影響に最も敏感であるようです.
定期的なモニタリングと言語に焦点を当てた早期の介入は,早産および早産の赤ちゃんに推奨されます.

キーワード:

ベイリーIII 神経発達時期が早かった出産前に期間について

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