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Updated: May 2, 2026

Viral Tracing of Genetically Defined Neural Circuitry
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ヒトの脳細胞型が宿主と狂犬病ウイルスの転写相互作用を形作っており,既にあるプロウイルス性アストロサイト亜集団を明らかにしている

Lena Feige1, Karl Young2, Juan Pablo Cerapio3

  • 1Institut Pasteur, Université Paris Cité, Lyssavirus Epidemiology and Neuropathology, 75015 Paris, France; Université de Paris Cité, 75015 Paris, France.

Cell reports
|August 27, 2025
PubMed
まとめ

狂犬病ウイルスの遺伝子発現は脳細胞の種類によって異なります. 予期せぬことに 免疫反応を阻害することで ウイルスのレベルが上昇し 神経性感染症における 星球細胞とマイクログリアの 保護的な役割が明らかになりました

キーワード:
CP: 免疫学CP: 神経科学アストロサイト宿主と病原体の相互作用マイクログリア神経ウイルス学狂犬病ウイルス単細胞RNA-seq

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