関連する実験動画

Updated: Sep 10, 2025

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
10:30

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

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ボトリヌム神経毒複合体のバイモジュール型のノットとボルト組成

Kwok-Ho Lam1, Linfeng Gao1, Adina Przykopanski2

  • 1Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA.

Science advances
|August 27, 2025
PubMed
まとめ

ボトリン神経毒複合体の構成は,BoNT/A-NTNH-HA70複合体の結晶構造を決定することによって解明された. これは,無毒の神経毒素関連タンパク質 (NTNH) がHA70に結合する方法を明らかにし,経口生物学的投与に関する洞察を提供している.

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Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays12:25

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays

Published on: March 3, 2014

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Analyzing Dynamic Protein Complexes Assembled On and Released From Biolayer Interferometry Biosensor Using Mass Spectrometry and Electron Microscopy09:30

Analyzing Dynamic Protein Complexes Assembled On and Released From Biolayer Interferometry Biosensor Using Mass Spectrometry and Electron Microscopy

Published on: August 6, 2018

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