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Updated: Sep 10, 2025

Predictive Immune Modeling of Solid Tumors
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Predictive Immune Modeling of Solid Tumors

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腫瘍免疫性に関する分子洞察

Irini Doytchinova1, Stanislav Sotirov1, Ivan Dimitrov1

  • 1Drug Design and Bioinformatics Lab, Faculty of Pharmacy, Medical University of Sofia, Dunav St. 2, 1000 Sofia, Bulgaria.

Current issues in molecular biology
|August 27, 2025
PubMed
まとめ

腫瘍の免疫原性を理解するには,T細胞のエピトープを特定する必要があります. この研究では,中央ペプチド領域の特定のアミノ酸パターンが,T細胞受容体 (TCR) の結合と免疫反応に不可欠であり,がんワクチン開発に役立ちます.

キーワード:
HLAクラスIの結合剤T細胞エピトープTCRベースの免疫療法免疫性について分子ダイナミクスシミュレーションネオアンチゲン予測ワクチンの設計

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