関連する実験動画

Updated: Sep 10, 2025

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
12:49

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

Published on: March 21, 2020

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[LRRK2遺伝子の変異と関連したパーキンソン病: 治療方法]

T S Usenko1,2,3, S N Pchelina1,2

  • 1Konstantinov St. Petersburg Nuclear Physics Institute, National Research Center Kurchatov Institute, Gatchina, 188300 Russia.

Molekuliarnaia biologiia
|August 27, 2025
PubMed
まとめ

レウシンに富んだリピートキナーゼ2 (LRRK2) は,パーキンソン病 (PD) の病原性において極めて重要です. LRRK2の構造とキナーゼの活性を理解し,特に変異がPDにどのように影響するかを理解することで,PDに対する新しい治療目標が提供されます.

キーワード:
LRRK2パーキンソン病パーキンソン病の治療機能構造

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