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Updated: Sep 10, 2025

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays
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Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

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薬剤発見におけるALK5キナーゼ阻害剤:構造的洞察と治療的応用

Fang-Yan Guo1, Siqi Li1, Changhao Zhang1

  • 1Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China.

European journal of medicinal chemistry
|August 27, 2025
PubMed
まとめ

アクティブリン受容体型のキナーゼ5 (ALK5) 阻害剤は,TGF-β経路を標的として,癌および線維症の治療に有望である. 研究は臨床候補物質や化合物や 心臓毒性などの課題を 最適な治療法として強調しています

キーワード:
ALK5 について癌についてキナーゼ合成TGF-β

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