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Updated: Sep 10, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
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エタクリン酸は,血液・迷宮障壁経由でゲンタミシンオトキシ性を調節する

Liling Li1, Jingqian Tan1, Dan Chen1

  • 1Department of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guang Zhou, Guangdong, China, 510630.

Hearing research
|August 27, 2025
PubMed
まとめ

エタクリン酸 (EA) はゲンタミシン (GM) の耳毒性を悪化させ,重度の聴覚障害を引き起こす. N-アセチルシステイン (NAC) は,特に早期に投与された場合,この損傷から保護し,薬物による聴覚障害を予防する戦略を提供します.

キーワード:
血液・迷宮の障壁エタクリン酸ジェンタミシンN-アセチルシステインオート毒性

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