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Updated: Sep 10, 2025

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
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抗うつ薬は,セロトニン強化された細胞表面結合によるリポプロテイン (a) マクロピノシトーシスを刺激する

Nikita Deo1, Halima Siddiqui1, Katie Peppercorn1

  • 1Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand; HeartOtago, University of Otago, Dunedin, New Zealand.

Journal of lipid research
|August 27, 2025
PubMed
まとめ

イミプラミン,シタロプラム,パロキセチンのような特定の抗うつ薬は,細胞表面結合を増やすことにより,リポプロテイン (a) [Lp (a) ]の吸収を予期せぬほど強化する. これは,セロトニン再吸収阻害剤 (SSRI) が,うつ病患者のLp (a) レベルを下げるのに役立つことを示唆している.

キーワード:
プラグイン脂質タンパク質 (a)マクロピノサイトーシスセロトニン再吸収阻害剤セロトニン

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