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Updated: Sep 10, 2025

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Syndecan-2は,乳がん細胞におけるWnt/β-カテニンのシグナル伝達を正に調節する

Leyli Naraghi1, Alexey Koval2, Vladimir L Katanaev2

  • 1Department of Cell and Molecular Biology, School of Biology, College of Sciences, University of Tehran, Tehran P.O.Box 14155-6455, Iran; Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

The international journal of biochemistry & cell biology
|August 27, 2025
PubMed
まとめ

癌の進行における重要な経路であるWnt/β-カテニンのシグナル伝達を強化します. この発見は,シンデカン-2 が特定の癌の腫瘍増殖を抑制する潜在的な治療標的であることを示唆しています.

キーワード:
BT-20 バイアスCRISPR-Cas9についてヘパラン硫酸タンパク質シンデカン-2トリプルネガティブ乳がんWnt/β-カタニンシグナリング

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