大人の乳がんにおける若者の食事摂取量:体系的なレビューとメタ解析

Gladys Huiyun Lim¹, Ying Cong Ryan Shea Tan², Ethan Lee¹

¹Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.

Advances in nutrition (Bethesda, Md.)

|August 27, 2025

まとめ

果物,野菜,大豆,繊維,野菜の豊富な食事は,成人の乳がんの危険を軽減するかもしれません. 青春期に繊維とビタミンDを多く摂取すると乳腺の良性疾患のリスクが低下します

科学分野:

腫瘍学
栄養学的流行病学
予防医療

背景:

乳がんの予防には青春期は重要な時期です組織が急速に発達するからです
既存の乳がん予防戦略は主に成人のデータに基づいています
乳がんのリスクに対する青少年の食事の影響を理解することは極めて重要です

研究の目的:

思春期の食事と成人期の乳がんリスクとの関連を体系的に検討し,メタ分析する.
乳児の栄養と良性乳房疾患 (BBD) とマンモグラフィの密度との関連を調べる
乳がん発症に影響するかもしれない青春期の食事の要因を特定する.

主な方法:

疫学研究の体系的なレビューとメタ解析
少女 (10歳から18歳) の研究を複数のデータベース (Web of Science,MEDLINE,Cochrane,Embase) で検索した.
ニューカッスル・オタワスケールを用いて研究の質を評価し,ランダム効果モデルを用いて結果をまとめました.

主要な成果:

青少年の果物/野菜,大豆,食物繊維,植物性脂肪の摂取量が増加すると大人の乳がんのリスクが低下する.
乳腺の良性疾患 (BBD) のリスクの減少と関連している.
肉,家禽,魚,卵,乳製品,穀物,アルコール,総脂肪,動物性脂肪,またはイソフラボンは有意な関連性が見つかりませんでした.

結論:

乳がんの予防に重要な役割を果たすのは青春期の食事パターンです
研究結果はタイミングと食生活が乳がんのリスクを軽減する上で重要であることを示しています
青少年の暴露に関する証拠を強化するために,高品質の将来の生涯の研究が必要です.

キーワード:

ティーンエイジャー乳がん乳腺疾患ダイエットメタ解析

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