関連する実験動画

Updated: Sep 10, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

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アピカル・ハイパルトロフィック・カルディオミオパシーにおけるフェノタイプの重複: "つのサイズがすべてに合わない"

Offdan Narvaez-Guerra1, Mina Botros2, Evan Offord2

  • 1Division of Cardiology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA offdannarvaez@gmail.com.

BMJ case reports
|August 27, 2025
PubMed
まとめ

このケースは,多様性イメージングが重複的な表型を持つ高縮性心筋病 (HCM) の管理にどのように重要かを強調しています. エコーカーディオグラフィーと心磁気共鳴 (CMR) は,アピカルHCM (ApHCM) の不良予後を示すサブクリニックマーカーを明らかにすることができます.

キーワード:
解剖学 的 変化心血管医学

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Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy I: Introduction and Classification

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Cardiomyopathy II: Dilated Cardiomyopathy

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Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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