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Updated: Sep 10, 2025

Application of an In vitro DNA Protection Assay to Visualize Stress Mediation Properties of the Dps Protein
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DNA 損傷における栄養ストレス

Jiali Jin1, Ping Wang2

  • 1Shanghai Tenth People's Hospital, School of Medicine, Tongji University Cancer Center, Tongji University, Shanghai 200092, China.

Trends in cell biology
|August 27, 2025
PubMed
まとめ

細胞は 栄養とDNAの損傷により ストレスにさらされ 機能に悪影響を及ぼします これらのストレスがどのように相互作用するかを理解することは 癌の研究と新しい治療法の開発の鍵です

キーワード:
DNA 損傷反応と修復ガン治療栄養ストレス栄養素を感知する経路

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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
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