関連する実験動画

Updated: Sep 10, 2025

Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood
06:07

Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood

Published on: February 5, 2020

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免疫 "チェックポイント" 療法 が 臨床 試験 の 大半 で 失敗 し た の は なぜ です か

Xuan Yang1, Lieping Chen2,3,4

  • 1Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA.

Journal for immunotherapy of cancer
|August 27, 2025
PubMed
まとめ

PD-1/PD-L1経路阻害剤の成功にもかかわらず,TIM-3やTIGITのような他のチェックポイント阻害剤の効果は限られている. このレビューは,これらの失敗の理由を探求し,がんの免疫療法のための戦略的な道を提案します.

キーワード:
免疫調節剤免疫抑制免疫療法腫瘍の微小環境 - TME

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