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デンドリット細胞特異のTNFR2をターゲットにすることで,皮膚と関節の炎症が改善される

Raminderjit Kaur1,2, Jean Lin3, Jennifer E Harvey1

  • 1Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, USA.

Scientific reports
|August 27, 2025
PubMed
まとめ

腫瘍死因α受容体2 (TNFR2) が dendritic 細胞 (DC) にシグナル伝達することで,牛皮質関節炎 (PsA) の発症を誘発する. DCにおけるTNFR2の阻害は,PSAのような炎症と炎症誘発性サイトカインの生成を減少させる.

キーワード:
デンドリット細胞牛皮病TNFα受容体について

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