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Updated: Sep 10, 2025

Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference
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Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference

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コカインの化学遺伝学は,合成生理学による薬物探求を鈍化させる

Juan L Gomez1, Christopher J Magnus2,3,4, Jordi Bonaventura1,5

  • 1Biobehavioral Imaging and Molecular Neuropsychopharmacology Section, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD, USA.

Nature
|August 27, 2025
PubMed
まとめ

研究者はコカイン中毒を食い止めるために 新種の合成生理学法を開発しました このアプローチでは コカインに誘発されたチャネルを使って 薬物によるドーパミンシグナル伝達を 選択的に減少させることで 依存症に対する遺伝子治療の 可能性が示されています

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