関連する実験動画

Updated: Sep 10, 2025

Profiling of Permethylated Mucin O-glycans Using Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry
08:51

Profiling of Permethylated Mucin O-glycans Using Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry

Published on: June 20, 2025

277

ムシンの模倣剤としての高分枝硫酸グリコポリマー

Melina I Feldhof1, Rebecca Schlatterer2, Friederike Strahl2

  • 1Department of Organic Chemistry and Macromolecular Chemistry, Heinrich-Heine-University Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany.

Journal of the American Chemical Society
|August 28, 2025
PubMed
まとめ

研究者は天然のムシンを模倣する 新種のダブルブラッシュ・グリコポリマーを開発しました これらの合成ムシンは 粘着性や形状などの 重要な性質を効果的に複製し 生物医学的な応用を進めています

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Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution11:39

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Glycosaminoglycans

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Protein Glycosylation01:25

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
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