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Updated: Sep 10, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

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空間トランスクリプトミクス 乳がん微環境の解読 異質性:多次元のダイナミックプロファイリングから精密セラピーブループリントの構築まで

Aolong Ma1, Lingyan Xiang1, Jingping Yuan1

  • 1Department of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

Biomolecules
|August 28, 2025
PubMed
まとめ

空間トランスクリプトミクス (ST) は乳がんの異質性と腫瘍微環境 (TME) を解読する. この技術は 細胞の相互作用を明らかにし 治療への反応を予測し 精密な腫瘍学への道を開きます

キーワード:
乳がん異質性について進行と転移空間トランスクリプトミクス治療法腫瘍の微小環境

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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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