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Updated: Sep 10, 2025

Establishing Cell Lines Overexpressing DR3 to Assess the Apoptotic Response to Anti-mitotic Therapeutics
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薬物の再利用スクリーンは,腫瘍抑制剤 DAB2IP の新しい調節剤として識別します

Rossella De Florian Fania1, Serena Maiocchi1,2, Raffaella Klima2

  • 1Department of Life Sciences, University of Trieste, Via L. Giorgieri 1, 34127 Trieste, Italy.

Biomolecules
|August 28, 2025
PubMed
まとめ

研究者らは,チオストレプトンを腫瘍抑制剤 DAB2IP (Disabled-2 相互作用タンパク質) のレベルを高める薬として特定した. DAB2IPを再活性化することは 攻撃的な癌の治療のための新しい戦略かもしれません

キーワード:
AIP1 についてCRISPR-Cas9についてFOXM1についてハイビットラス・ギャップ高通量スクリーニング前立腺がんタンパク質のタグ付け腫瘍抑制遺伝子

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