離乳児 の 成長,酸化 ストレス,免疫 機能 に 対する イヌリン の 影響
Zhiling Zhou1, Chunmei Du1, Pengxin Wu1
1College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China.
Animals : an open access journal from MDPI
|August 28, 2025
まとめ
イヌリン補給は,特に0. 3%で,離乳ヤギの成長,免疫機能,腸の健康を大幅に改善しました. この飼料添加物は,抗酸化能力を高め,炎症を軽減し,全体的な発達を促進します.
科学分野:
- 動物科学
- 栄養学
- 羊の生産
背景:
- 早期に離乳したヤギは ストレスにさらされ 成長や発達に 影響を及ぼします
- 飼料添加物は,若いヤギのストレス軽減とパフォーマンスの向上に不可欠です.
研究 の 目的:
- 乳児の成長,免疫,腸の健康に対するインリンの影響を調査する.
- 子供のパフォーマンスを改善するために最適のイヌリンの投与量を決定します.
主な方法:
- 30匹の60日目の離乳児は,対照群,オーレオミシン塩化物,および3つのインリン補給レベル (0. 1%, 0. 3%, 0. 5%) と5つのグループに分けられました.
- 成長性能,免疫指標 (sIgA,IgA,IgG),抗酸化活動,セカルの揮発性脂肪酸,ヘジュナル酵素活動,遺伝子発現 (緊密な結合タンパク質,炎症因子) を分析した.
主要な成果:
- 0. 3% のイヌリン補給は,オーレオミシン水塩化物と同等の最終的な重量をもたらした.
- イヌリンは,免疫指標,抗酸化作用,全身の揮発性脂肪酸,腸の消化酵素作用を有意に増加させた (p < 0. 05).
- イヌリンはタイトジャンクションタンパク質 (TJP1,OCLN) と抗炎症因子 (TGF-β1,IL-10) を上調し,乳首のIL-6を下調した (p < 0. 05).
結論:
- イヌリン補給は,離乳したヤギの成長能力,抗酸化能力,免疫反応を高めます.
- イヌリンは酵素活動,揮発性脂肪酸,炎症反応を調節することで腸の健康を改善します.
- 離乳後の黒山羊の成長と生理学的パラメータを改善するための最適な用量として,0. 3%のイヌリンが特定されています.
関連する概念動画
01:23Anatomy of the Intestines
65.2K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
65.2K
01:15Transcytosis of IgG
3.4K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
3.4K
01:22Development of Immunocompetence
1.2K
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
1.2K
01:23Stringent Response in E. coli
528
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
528
01:30Development of Human Microbiota
61
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
61
01:28Development of the Oral Microbiota
65
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
65