口腔の微生物群および関連する全身疾患に対する消毒剤の効果: スコーピングレビュー
Angela Angjelova1, Elena Jovanova1, Alessandro Polizzi1,2
1Unit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95123 Catania, Italy.
Antibiotics (Basel, Switzerland)
|August 28, 2025
まとめ
口腔用消毒剤は病原菌と闘うが,口腔の微生物群を破壊し,全身の健康に影響を与える可能性がある. これらの効果を理解し,より安全な口腔衛生戦略を開発するには,さらなる研究が必要です.
科学分野:
- 口腔微生物学
- 組織的健康
- 消毒剤
背景:
- 口服用消毒剤は,病原体制御のための衛生で一般的です.
- その使用は口腔の微生物群のバランスを乱し,全身的な健康への影響を及ぼす可能性があります.
- 消毒剤の使用,微生物の変化,および全身的な結果の間のリンクは,さらなるマッピングを必要とします.
研究 の 目的:
- 口腔の微生物群の組成に対する消毒効果の証拠を調査する.
- 消毒剤の使用と全身疾患の潜在的な関連を調べる.
主な方法:
- 2025年6月までのPubMed,Scopus,Web of Scienceのスコーピングレビュー
- 含まれている研究では,一般的な口腔消毒剤 (クロルヘキシジン,エッセンシャルオイル,セチルピリジニウム塩化物) が調査されました.
- 12件の研究から抽出された研究設計,薬剤,微生物のアウトカム,およびシステミックな影響に関するデータ.
主要な成果:
- 口服用消毒剤は病原体を効果的に減らし,口腔疾患 (歯周炎,歯周炎) のアウトカムを改善します.
- 微生物の共同体の変異と潜在的ディスバイオシスが報告されました.
- 消毒剤による微生物変化と全身疾患 (心血管,呼吸器) の間の関連が示唆された.
結論:
- 口服用消毒剤は,病原体の制御に有益ですが,微生物の恒常性を破壊する可能性があります.
- 障害は有害な全身的な結果をもたらす可能性があります.
- 長期的な効果を評価し,微生物群を保全する口腔衛生戦略を開発するには,さらなる研究が不可欠です.
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