関連する実験動画

Updated: Nov 13, 2025

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation
07:26

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

8.2K

新しいバイオエンジニアリングのテストベッドを使用して,チューインガムから有効な薬物放出のための2バイトテストパラメータの実験研究

Kazem Alemzadeh1, Joseph Alemzadeh2

  • 1(ESDI) Bionics and Bioengineering Research Group, Faculty of Engineering, School of Electrical, Electronic and Mechanical Engineering, University of Bristol, Bristol BS8 1TR, UK.

Biomedicines
|August 28, 2025
PubMed
まとめ

この研究では,薬効性チューインガム (MCG) の薬物放出を分析するための新しいチューインロボットとテストベッドを導入します. 結果は,の生理学と歯の形状が,の効率と有効な薬剤成分 (API) の放出にどのように影響するかを明らかにしています.

キーワード:
FMAとBAの角度についてバイオミメティック・チューイング・チャンバークラッシュ/シェア比歯の形状との生理効率的な噛みしめ人間型の噛むロボット機械化学薬効性のあるガム閉ざされた歯茎二回噛み合いのテスト

さらに関連する動画

Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals04:28

Utilizing an Orally Dissolving Strip for Pharmacological and Toxicological Studies: A Simple and Humane Alternative to Oral Gavage for Animals

Published on: March 23, 2016

12.8K
A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration11:16

A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration

Published on: February 6, 2014

12.8K

関連する概念動画

In Vitro Drug Dissolution: Compendial Testing Models II01:09

In Vitro Drug Dissolution: Compendial Testing Models II

Various dissolution methods are utilized to assess a drug’s dissolution rate, including the flow-through cell, paddle-over-disk, cylinder, and reciprocating disk methods.The flow-through cell apparatus (USP (United States Pharmacopeia) method 4) comprises a reservoir for the dissolution medium and a pump that propels the medium through the cell containing the test sample. This method is crucial for assessing modified-release dosage forms with minimally soluble active ingredients,...
63
In Vitro Drug Dissolution: Compendial Testing Models I01:13

In Vitro Drug Dissolution: Compendial Testing Models I

Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
83
In Vitro Drug Dissolution: Alternative Methods01:17

In Vitro Drug Dissolution: Alternative Methods

Alternative drug dissolution methods include the rotating bottle, intrinsic dissolution test, peristalsis, and the Franz diffusion cell method. The rotating bottle method involves meticulously rotating tightly capped controlled-release beads in a temperature-controlled bath. Periodic decanting of samples allows for residue assay, followed by refilling with fresh medium and testing at various pH levels to emulate the gastrointestinal tract conditions.In contrast, the intrinsic dissolution test...
72