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Updated: Sep 10, 2025

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds
12:32

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds

Published on: January 23, 2018

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ラミュルス・モリ (Sangzhi) アルカロイドは,腸内微生物およびイントラ・アイレットの2-メトキシエストラジオール生物合成により,臓β細胞機能を改善する

Nan Wu1, Lusi Lu1, Yiming Liu1

  • 1Department of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.

Biomedicines
|August 28, 2025
PubMed
まとめ

サンジアルカロイド (SZ-A) は,腸内細菌を2メトキシエストラディオル (2-ME) を増加させるように調節することによって,2型糖尿病を改善します. この代謝物は,HIF- 1αのシグナル伝達を抑制することで,インスリン分泌を促進し,ベータ細胞の機能を回復させます.

キーワード:
2-メトキシエストラジオールラミュルス・モリ (Sangzhi) アルカロイド腸内微生物群メタボライトβ細胞の機能

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