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Updated: Sep 10, 2025

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
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遺伝子ポリモルフィズムにおけるOCT1とMAP3K5の役割

Sarah Allegra1, Giuliana Abbadessa1, Francesco Chiara1,2

  • 1Clinical Pharmacology, Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.

Life (Basel, Switzerland)
|August 28, 2025
PubMed
まとめ

OCT1の遺伝的変異は,状細胞疾患の患者におけるヒドロキシウレア薬の半減期に影響を与える. 性別や民族を考慮した この薬剤遺伝学的洞察は 治療の個性化により より良い結果をもたらします

キーワード:
MAP3K5 についてオーケストラハイドロキシカルバミド薬剤遺伝学

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