関連する実験動画

Updated: Sep 10, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

7.0K

統合的高通量RNAiスクリーニングは,BRSK1,STK32CおよびSTK40をYAP/TAZの新規活性化剤として識別する

Mandeep K Gill1, Siyuan Song1, Tania Christova1

  • 1Department of Biochemistry, Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada.

International journal of molecular sciences
|August 28, 2025
PubMed
まとめ

研究者は,高通量スクリーンを用いて,トリプルネガティブ乳がん (TNBC) の新しいYAP/TAZのレギュレータを特定しました. これらの発見は,ヒッポの経路を標的としてTNBCの新たな治療戦略につながる可能性があります.

キーワード:
AMPKファミリーメンバーBRSK1 について海馬の経路RNAiスクリーニングSTK32CSTK40 についてYAP/TAZトリプルネガティブ乳がん

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A Rapid In Vivo Bioassay for Developmentally Active Enhancers

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Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation09:07

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation

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