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Updated: Sep 10, 2025

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
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コロナウイルスに対するサイクロフィリン阻害剤の広範な抗ウイルス活性:体系的なレビュー

Abdelazeem Elhabyan1,2, Muhammad Usman S Khan1, Aliaa Elhabyan3

  • 1Institute for Regeneration and Repair, University of Edinburgh, Edinburgh EH16 4UU, UK.

International journal of molecular sciences
|August 28, 2025
PubMed
まとめ

サイクロフィリン阻害剤は,サイクロスポリンAのように,コロナウイルスに対する広範囲の抗ウイルス活性を示します. これらの化合物は,ウイルス負荷を効果的に軽減し,動物モデルとヒト臨床試験の両方で結果を改善します.

キーワード:
HCoV-229EについてMERS-CoV ウイルスSARS-CoV についてSARS-CoV-2についてアリスポリビール広範囲の抗ウイルス薬コロナウイルスサイクロフィリン阻害剤サイクロスポリンAウイルスの複製

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